ZenFlora
GHK-Cu Anti-Aging & Skin Repair Peptide
GHK-Cu Anti-Aging & Skin Repair Peptide
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GHK-Cu Peptide is a naturally occurring human copper-binding tripeptide (glycyl-L-histidyl-L-lysine) that has been studied extensively for its regenerative and protective properties. It is widely used in anti-aging cosmetic products due to its beneficial effects on skin and hair.
Chemical structure and function
- GHK-Cu is a small, naturally occurring molecule present in human plasma, saliva, and urine.
- The tripeptide GHK has a strong affinity for copper (II) ions and readily forms the GHK-Cu chelate.
- Plasma GHK levels decline with age, with average levels decreasing by over half by age 60. This decline coincides with the body's reduced regenerative capacity.
GHK-Cu promotes healing and rejuvenation through several pathways:
- Regulates gene expression: It modulates the expression of numerous human genes, essentially resetting gene patterns to a healthier state.
- Increases synthesis of proteins: It stimulates the production of collagen and elastin, which improves skin firmness and elasticity.
- Exhibits antioxidant and anti-inflammatory effects: It helps protect cells from damage caused by free radicals and reduces inflammation.
- Boosts wound healing: It attracts immune and endothelial cells to injury sites, accelerates wound healing, and promotes the repair of protective skin barrier proteins.
- Promotes angiogenesis: It stimulates the formation of new blood vessels, which improves the delivery of nutrients and oxygen to tissues.

Benefits of GHK-Cu
Studies and use in cosmetic products have shown GHK-Cu to be beneficial for:
- Skin:
- Reducing the appearance of fine lines, wrinkles, and sun damage.
- Improving skin firmness, elasticity, and clarity.
- Tightening loose skin and smoothing rough skin texture.
- Accelerating wound healing and repairing damaged tissue.
- Hair:
- Stimulating hair growth and increasing hair thickness.
- Enlarging hair follicle size.
- Potentially inhibiting the activity of 5 alpha reductase, which is associated with hair loss.
- Systemic health:
- Protecting against oxidative stress and inflammation.
- Preliminary observations in animal studies suggest it may help reverse age-associated cognitive decline.
GHK-Cu is most commonly used in topical cosmetic products like creams, serums, and masks. Injections are also available and are typically administered by a professional.
Potential side effects and considerations
While generally considered safe, some users may experience side effects, especially at higher concentrations:
- Skin irritation: Mild irritation, redness, or itching can occur, particularly when first starting use.
- Copper overload: This is rare with standard topical use but possible with excessive use of multiple copper-containing products. Symptoms may include abdominal pain or nausea.
- Contraindications: Those with active cancer should consult a physician before use, as GHK-Cu stimulates blood vessel formation, which tumors require to grow.
- Ingredient interactions: GHK-Cu may interact with certain skincare ingredients like vitamin C and retinol, potentially reducing effectiveness or increasing sensitivity.
Suggested Dosage :
- Typical doses range from 1 mg to 2 mg daily (standard)
Disclaimer:
For external or professional use only. Consult a healthcare professional before use if you have sensitive skin or medical concerns.

Product Set Inclusion:
-
Bacteriostatic Water
-
Reconstitution Syringe
-
Insulin Syringe
- Alcohol Pads
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